should you take calcium supplements with prolia

Youll receive Prolia from a healthcare professional as an injection under the skin in one of the following areas: Prolia contains the active drug denosumab, which is a biologic medication. If the side effects seem life threatening or you think youre having a medical emergency, immediately call 911 or your local emergency number. Find out what it means, how its calculated, and more. (To learn more, see the Precautions for Prolia section below.). Problem absorbing minerals. Its thought that hair loss could occur due to how Prolia affects your immune system. Like most drugs, Prolia may cause mild or serious side effects. Before starting Prolia treatment, talk with your doctor about any tooth procedures you have scheduled. Your doctor or another healthcare professional will inject Prolia under the skin in one of the following areas: Prolia doses are given as an injection by healthcare professionals once every 6 months. Your risk may also be higher if you: Stopping Prolia treatment can also increase your risk for bone fractures. Calcium supplements may help support bone and teeth health. Both are prescription medicines. Do not stop, skip or delay taking Prolia without first talking with your doctor. Theyll discuss with you other treatments to help protect you from fractures and bone loss. BMD was increased by 8.8% at the lumbar spine, 6.4% at the total hip, and 5.2% at the femoral neck in trials that measured BMD after three years of treatment with Prolia. Studies have found that Prolia is generally safe and effective to treat osteoporosis and certain types of bone loss. Is the ketogenic diet right for autoimmune conditions? The drug could cause your calcium level to drop too low. Before you have any dental work done, tell your dentist you are receiving this medicine. They do this by slowing the loss of minerals such as calcium from your bones. Sciatica is described as a shooting pain that travels from the lower back down a leg. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Your FRAX score is your risk of having an osteoporosis-related fracture in the next 10 years. As with most drugs, Prolia can cause an allergic reaction in some people. Store in the original container away from heat and light. Additionally, in Prolia-treated men with nonmetastatic prostate cancer receiving ADT, a greater incidence of cataracts was observed. 2023 Healthline Media UK Ltd, Brighton, UK. Prolia may lower the calcium levels in your blood. If youve already gone through menopause, your risk for bone loss is increased. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. They can help answer any questions you have about side effects from taking the drug. If you have serious side effects from Prolia, call your doctor right away. For Prolia, talk to your pediatrician regarding the use of this medicine in children. What do I need to be aware of if I need a tooth extraction while Im using Prolia? And some of these side effects are more common with certain uses of Prolia. If you develop hypocalcemia, your doctor will typically have you stop using Prolia. It is important for you to practice good mouth care during treatment with Prolia. But certain choices and habits accelerate the process. It does the same thing that. low calcium level--muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes). (Biosimilars are like generic drugs. Call your doctor or health care professional if you are unable to keep an appointment. The phase IV clinical study analyzes what interactions people who take Prolia and Calcium have. Whats the Connection Between Estrogen and Osteoporosis? Prolia is a prescription medicine used to treat bone loss in men who are at high risk for fracture receiving certain treatments Prolia pregnancy and breastfeeding warnings. Vertigo (dizziness) was reported in some females* using Prolia for osteoporosis. You should also talk with them if you have any serious side effects during Prolia treatment. Coral calcium is also used in maxillofacial surgery and bone grafting. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. This is the drugs mechanism of action. Learn more about the unique risk factors for osteoporosis in, Osteoporosis weakens bones, which leads to breaks in the hips, wrists, and spine. To help prevent low calcium, your healthcare provider may also They need to know if you have any of these conditions: This medicine is for injection under the skin. To date, the consensus is that there has been no proven risk of increased cardiovascular risk with intake of calcium supplements. Your doctor may also recommend other treatments with Prolia to help increase your bone mass. For this reason, some calcium supplements are combined with vitamin D. This vitamin is available in two forms, vitamin D 2 (ergocalciferol) and vitamin The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Most Medicare plans and other insurance plans cover Prolia. If youve had surgery on your thyroid or parathyroid glands, you may have an increased risk of a low level of calcium in your blood. But this isnt the case with Prolia. But doing so can cause more bone breakdown and increase your risk for bone fractures. What's the difference between Prolia and Reclast? Theyll also discuss with you how to lower your risk for fractures by adding other treatments or making certain lifestyle or diet choices. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. The list below may not include all possible serious side effects of the drug. With osteopenia, your bone mineral density (BMD) is lower than usual. Do not reuse a needle or syringe. Here are a few questions to consider asking your doctor: You can also learn more about osteoporosis treatment options here. Serious side effects that have been reported and their symptoms include: * To learn more, see Does Prolia cause long-term side effects? in the FAQs about the side effects of Prolia section below. You should take calcium and vitamin D as your doctor tells you to while you receive Prolia. Before you start Prolia treatment, your doctor will examine the inside of your mouth. Your doctor can also help you decide if the benefits of Prolia treatment outweigh your risks of side effects. Talk with your doctor about your health history and discuss your risks with Prolia treatment. If you have any questions about Prolias side effects, talk with your doctor. If you drink alcohol, talk with your doctor about how much is safe to drink with your condition. You may need to have a negative pregnancy test before starting this treatment. Others may continue for as long as you take the drug, but they can be easily managed. Stopping Prolia doesnt cause withdrawal symptoms. And ask your doctor about which drug is right for your condition. All rights reserved. Prolia contains the active drug denosumab, and Reclast contains the active drug zoledronic acid. So your healthcare provider will likely ask you to take calcium and vitamin D supplements if youre not taking them already. Had parathyroid or thyroid surgery (glands located in your neck), Have been told you have trouble absorbing minerals in your stomach or intestines (malabsorption syndrome), Have kidney problems or are on kidney dialysis, Are taking medicine that can lower your blood calcium levels, Plan to have dental surgery or teeth removed, Are breast-feeding or plan to breast-feed. You should also talk with your doctor if you have nausea during treatment. WebStudies have shown that people who live more sedentary lifestyles are at an increased risk of developing osteoporosis. Prolia is injected under the skin. They can give you more details about this possible side effect and suggest ways to manage it. Because Prolia can also cause low blood calcium, your risk may increase if you receive Prolia. But its not clear how often this side effect occurred in clinical trials. This may help to protect healthy cells from damage. if you are taking medicine that lower your blood calcium levels. You should take calcium and vitamin D as your doctor tells you to while you receive Prolia. Serious infections may occur during treatment with Prolia. They may also have you see your dentist. Here are a few tips that might help guide your discussion: Remember, your doctor and other healthcare professionals are available to help you. Over time, Prolia can reduce bone loss and make your bones stronger. You should make sure you get enough calcium and vitamin D while you are taking this medicine, unless your doctor tells you not to. Prolia also has other uses, which are described in the next section below. (A low blood calcium level is a possible side effect of Prolia.). Xgeva is also used to treat giant cell tumor of the bone. These problems may include: Your risk for mouth-related side effects may be higher if you have problems with your teeth. WebProlia is used to treat osteoporosis in women after menopause and in men, and in people However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Over time, Prolia helps to improve the density and strength of your bones by slowing bone loss. If you receive Prolia, you should not receive XGEVA. They can tell you more about benefits and risks of Prolia and Forteo. But nausea may be a symptom of side effects such as vertigo or constipation. Talk with your doctor about which medication is right for you. Learn more details about some of the side effects that Prolia may cause. WebAdults ages 19 through 50 should not get more than 2,500 mg calcium total per day (including food and supplements). They may help you identify other possible causes or suggest ways to help manage hair loss. Osteoporosis Is Common in Older Men, Know the Risks, Your Guide to Osteoporosis and Broken Bones: Know Your Risks, 7 Things You Can Do Today to Prevent Osteoporosis, treat osteoporosis in males* and in females* whove gone through, treat osteoporosis caused by long-term use of, increase bone mass in females using certain, increase bone mass in males using certain treatments for, increased risk of bone fracture after stopping Prolia treatment, such as having multiple, severe pain in your joints, bones, and muscles, skin-related side effects, such as rash, dry skin, or blisters, decreased bone production, which means your bones take longer to make new bone tissue, dental problems and jaw-related side effects*, jaw necrosis (death of tissue in the jawbone), Prolias active ingredient is denosumab. Symptoms can be mild or serious and can include: For mild symptoms of an allergic reaction, call your doctor right away. These are serious. Your doctor can help you decide which drug is better for your needs. Thyroid or parathyroid surgery. You may wonder how Prolia compares to the medication Zometa. To learn more about this side effect, see Side effect specifics below. And theyll recommend if its the best option for your condition. Our phase IV clinical studies alone cannot establish cause-effect relationship. Other drugs may interact with denosumab, including prescription and over-the-counter medicines, vitamins, and herbal products. In addition to treating osteoporosis, which is described just above, Prolia also has other uses. Some side effects of Prolia may go away on their own within a few days or weeks after starting treatment. But if youre planning to have surgery, you may need to take a break Prolia may lower the level of calcium in your blood. For more information about the uses of Prolia, see the Is Prolia used for osteoporosis? and Is Prolia used for other conditions? sections below. Your risk of bone fractures can increase when you stop, skip or delay using Prolia. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Dietary calcium is considered safe, but too much calcium in the form of supplements might have some health risks. Tell your doctor right away if you become pregnant while taking Prolia. Bisphosphonates, on the other hand, help increase bone thickness and prevent bone breakdown. Policy. For instance, if you have a health condition that causes excess calcium in For example, if you have a serious UTI or other infection, call your doctor right away. If youre concerned about unexplained weight gain while using Prolia, talk with your doctor. Mild side effects can occur with Prolia use. More than half of American adults take an herbal or dietary supplement, and many more use over-the-counter or prescription drugs to manage maladies ranging from the occasional headache to chronic health conditions or mood disorders.. For many, it is part of their daily routine. Before taking Prolia, tell your doctor about all of your medical conditions, including if you: Your healthcare provider should do a pregnancy test before you start treatment with Prolia. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are receiving this medicine. The Prolia is making my leg bones and jaw bones hurt. If you have bothersome or severe side effects or other problems while taking Prolia and need to stop the medication, your doctor will monitor your bone mineral density. If youre concerned about weight gain with Prolia, talk with your doctor. They will also explain how much youll be given and how often. They can treat the infection as needed. * Sex and gender exist on spectrums. Learn how estrogen affects bone health and how you can protect yourself from bone loss, Osteoporosis is more common in women than men, but it affects millions of men every year. It is created by eHealthMe based on reports of 8,432 people who take Prolia and Calcium from the FDA, and is updated regularly. You might be interested in seeing how Prolia and the drug Boniva compare. The conditions and factors to consider include: Upcoming dental procedures. Breastfeeding. 12 Low serum calcium levels should be corrected before starting denosumab; supplemental calcium and vitamin D is required in patients predisposed to hypocalcaemia (see Ensure adequate calcium and vitamin D intake ). They include bone pain, back pain, and a higher risk of certain infections. Prolia isnt approved to treat osteopenia or arthritis. Some people have developed unusual fractures in their thigh bone. If youd like a detailed comparison of Prolia versus Boniva, view this article. Also, its important to brush and floss your teeth regularly while youre using Prolia. 1 shot every 6 months could mean fewer doses. You should not breastfeed while using this medicine. Prolia is a medicine that may affect the ability of your body to fight infections. Serious side effects of Prolia that have been reported include: For most people, Prolias side effects are mild and go away after a few days to a few weeks. But if you think youre having a medical emergency, call 911 or your local emergency number. Monoclonal antibodies are made to target and destroy only certain cells in the body. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. To learn about other mild side effects, talk with your doctor or pharmacist, or read Prolias medication guide. High cholesterol levels can be a side effect of Prolia. Below, we answer some common questions about taking Prolia. The drug may also be used off-label for osteopenia, but usually, you dont need medications for osteopenia. The most common side effects of Prolia in patients receiving certain treatments for prostate or breast cancer are joint pain, back pain, pain in your arms and legs, and muscle pain. It is advisable to take 2 capsules in the morning with food and 1 in the evening also with food. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. It can have some side effects, but these may depend on who uses it. Continue reading, Prolia is a prescription medicine injected under the skin (called a subcutaneous injection) and is given once every 6 months. Common Your low blood calcium must be treated before you receive Prolia. These effects are called interactions. (A placebo is a treatment with no active drug.). Be sure to talk with your doctor about which medication is right for you. American Dental Association (ADA) recommendations say that tooth extractions are allowable if needed during Prolia treatment, if both you and your dentist agree. Although both drugs are approved to treat similar conditions, they work in different ways. Symptoms of a severe allergic reaction can include swelling under your skin, typically in your eyelids, lips, hands, or feet. You might wonder how Prolia and the drug Xgeva compare. These lists dont include all possible side effects. After your treatment with Prolia is stopped, or if you skip or delay taking a dose, your risk for breaking bones, including bones in your spine, is increased. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. After you have taken Prolia out of the refrigerator, you may keep it at room temperature for up to 14 days. If the user is trying to grow bone due to osteoporosis, osteopenia, or any reason, the recommended intake is 4 capsules divided into 2 doses also taken in the morning and evening with food. Studies of Prolia didnt report weight gain as a side effect of the drug. It is based on denosumab and calcium (the active ingredients of Prolia and Calcium, respectively), and Prolia and Calcium (the brand names). The most common medications prescribed to lower cholesterol are statins. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. But Prolia is given once every 6 months by a healthcare professional. Before you start Prolia treatment, talk with your doctor about how long Prolias side effects may last. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Use of the term male in this article refers to sex assigned at birth. This increases your risk for bone fractures. Please know that the sponsors of this site are not responsible for content on the site you are about to enter. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. These factors include what your insurance plan covers. to treat osteoporosis in males* and in females* whove gone through, to treat osteoporosis caused by long-term use of, metabolic bone disease, such as Hajdu-Cheney syndrome and juvenile. Xgeva is used to treat a high calcium level due to cancer and to prevent bone fractures and other bone problems caused by multiple myeloma or cancer bone metastases. If youre concerned about hair loss with Prolia, talk with your doctor. For more information about how these medications compare with each other, ask your doctor. WebYou should take calcium and vitamin D as your doctor tells you to while you receive Call your doctor right away if you have signs of infection such as: swelling, pain, tenderness, warmth, or redness anywhere on your body; pain and burning when you urinate, painful urination; bladder infection (painful or difficult urination); lung infection (cough, shortness of breath); cold symptoms such as stuffy nose, sneezing, sore throat; This is not a complete list of side effects and others may occur. More common side effects in females* who received Prolia for osteoporosis after menopause included: More common side effects in males* who received Prolia for osteoporosis included: More common side effects in people who received Prolia for osteoporosis due to drugs called glucocorticoids included: More common side effects in people who received Prolia to stop bone thinning due to certain cancer treatments included: For a complete list of all the side effects reported with Prolia, see the drugs prescribing information. If youd like more information about Prolia use during pregnancy or while breastfeeding, talk with your doctor. But Zometa contains the active drug zoledronic acid. It is important to check supplement labels to ensure that the product meets United States Pharmacopeia (USP) standards. These treatments may include acetaminophen (Tylenol) or ibuprofen (Advil, Motrin). Find out which foods can help. What should I know about Prolia vs. Reclast? While youre receiving Prolia treatment, your doctor will monitor your cholesterol levels with regular blood tests. You may report side effects to FDA at 1-800-FDA-1088. Youll receive Prolia doses from a healthcare professional. Prolia isnt known to cause any harmful interactions with alcohol. (With off-label use, a drug is used to treat conditions other than those its been approved to treat.) For a basic overview of Prolia, including details about its uses, see this article. If your doctor says this is safe for you, youll be shown how to inject the medication. Prolia is a prescriptionmedicine used to treat bone loss in women who are at high risk for fracture receiving certain treatments for breast cancer that has not spread to other parts of the body. What should be considered before taking Prolia? Having dental procedures, including tooth extractions, during Prolia treatment may increase your risk of dental side effects. Do not stop, skip or delay taking Prolia without first talking with your doctor. Will my fracture risk come back if I stop Prolia treatment? This medicine is only given in a clinic, doctor's office, or other health care setting and will not be stored at home. Prolia contains the active ingredient denosumab. Prolias manufacturer also provides some self-injection instructions, as well as a video to show you how to inject Prolia. All subjects in the clinical trials of Prolia received 800mg of calcium and Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Continue reading, Prolia (denosumab) does increase bone density. Rare, long-term side effects of Prolia include fractures of the spine or femur (thighbone). Find out why people need calcium, which foods provide it, and what happens if they consume. Although very rare, Prolia can cause serious dental problems and jaw-related side effects. Although its rare, your doctor may give you the option to self-inject Prolia at home. With osteoporosis, your bones become porous, meaning there are large holes within your bone tissue. Nausea can sometimes be a symptom of severe constipation. I am taking Prolia and just saw that it's important to take Calcium because Prolia takes the calcium out of the blood and that can cause problems. Prolia may cause serious side effects. You can also visit the Prolia manufacturers website to see if they have support options. Get the treatment that fits your lifestyle, Stay informed with courtesy reminders, recipes and so much more. Your doctor will recommend the dosage of Prolia thats right for you. It is often used in osteoporosis. While youre taking Prolia, your healthcare provider will also strongly suggest taking at least 1000 mg of calcium and 400 international units (IU) of vitamin D daily to prevent hypocalcemia or low calcium levels. What is the most important information I should know about Prolia? These side effects include: Your risk for these serious side effects may be higher if youre older and have certain dental procedures. You will receive your Prolia injection from your healthcare provider at a their office or clinic. If youre able to become pregnant, your doctor will have you take a pregnancy test before you start Prolia treatment. But before taking Prolia, be sure to tell your doctor about all medications you take (including prescription and over-the-counter types). Learn about the different options, including the benefits of each and any potential side, A FRAX score can help predict the risk of fractures in people with osteoporosis. Prolia injections administered by a healthcare professional. If your dizziness doesnt go away or becomes severe, talk with your doctor. Tell your doctor about all other medicines you use. After your treatment with Prolia is stopped, or if you skip or delay taking a dose, your risk for breaking bones, including bones in your spine, is increased. To learn more about this, see the How is Prolia administered? section below. Coming to a Cleveland Clinic location?Hillcrest Cancer Center check-in changesCole Eye entrance closingVisitation and COVID-19 information, Notice of Intelligent Business Solutions data eventLearn more. Inflammation of the inner lining of the heart (endocarditis) due to an infection may also happen more often in people who take Prolia. If youre breastfeeding, you should not receive Prolia. Prolia is a prescription medicine used to treat bone loss in men who are at high risk for fracture receiving certain treatments for prostate cancer that has not spread to other parts of the body. Low blood calcium level. The lists below describe some of the more common side effects that Prolia may cause. See additional information. Allergic reaction. How long will the side effects of Prolia last? This list doesnt include all possible mild side effects of the drug. Theres no information available to know whether Prolia is passed into breast milk or if its safe to take while breastfeeding. It may not cover all possible information. Prolia may cause several side effects. such as inflammation of your skin (dermatitis), rash, and eczema have been reported. Its not known if Prolia is safe or effective for use in children. Get useful, helpful and relevant health + wellness information, 9500 Euclid Avenue, Cleveland, Ohio 44195 |, Important Updates + Notice of Vendor Data Event, low levels of calcium or Vitamin D in the blood, an unusual reaction to denosumab, other medicines, foods, dyes, or preservatives, medicines that lower your chance of fighting infection, steroid medicines like prednisone or cortisone, allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue, signs and symptoms of infection like fever or chills; cough; sore throat; pain or trouble passing urine, signs of low calcium like fast heartbeat, muscle cramps or muscle pain; pain, tingling, numbness in the hands or feet; seizures. Vertigo (dizziness) was reported in some people who received Prolia for osteoporosis, but this was a less common side effect. Xgeva is another brand of denosumab that treats high calcium levels caused by cancer and prevents bone breaks. The risk is real, but rare. Xgeva is another brand of denosumab used to prevent bone fractures and other skeletal conditions in people with tumors that have spread to the bone. MNT is the registered trade mark of Healthline Media. For a detailed breakdown of Prolia versus Xgeva, check out this article. Your doctor should examine your mouth before you start Prolia and may tell you to see your dentist. Also tell them if you smoke, drink alcohol, or use illegal drugs.

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